Germacrene synthase
WebJul 12, 2016 · Analogously, germacrene C synthase from Solanum lycopersicum clone pLE11.3 was also shown to accept more than one substrate, producing germacrene C (64%), germacrene A (18%), germacrene B (11%), and germacrene D (7%) with FDP, and limonene with GDP (Colby et al., 1998). TABLE 1. WebNov 22, 2013 · An additional sesquiterpene synthase (germacrene A synthase) has been cloned from A. annua but this enzyme was not included in the promoter studies. The cloned promoters have been fused to the GUS reporter gene and transgenic A. annua plants expressing these fusions have been established. Here we report on studies on the …
Germacrene synthase
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WebAug 11, 2024 · Germacrene A (GA) is a key intermediate for the synthesis of medicinal active compounds, especially for β-elemene, which is a broad-spectrum anticancer drug. … WebJul 28, 2012 · A putative gene encoding germacrene D synthase (GenBank Accession No. JQ247185) from tea plant (Camellia sinensis) was isolated by rapid amplification of …
WebDespite their importance, only four terpene synthases have been identified from the Zingiberaceae family: (+)-germacrene D synthase and (S)-β-bisabolene synthase from ginger rhizome, and α-humulene synthase and β-eudesmol synthase from shampoo ginger (Zingiber zerumbet) rhizome. We report the identification of 25 mono- and 18 … WebMay 22, 2024 · Germacrene A synthase (GAS) catalyses a 1,10-cyclisation of FPP to B, followed by deprotonation to 1 (Scheme 3). Both enantiomers of 1 are accessible through this reaction, depending on whether C10 of …
WebDec 16, 2008 · Sesquiterpene synthase that catalyzes the formation of germacrene A. Can use farnesyl diphosphate as substrate, but not geranyl diphosphate or geranylgeranyl diphosphate. Beta-elemene, the initially measured product in the assay, is derived nonenzymatically from germacrene A. 1 publication WebGermacrene D Receptor Neurons. One type of receptor neurons, tuned to the sesquiterpene germacrene D, frequently occurred in recordings from heliothine moths, …
WebNeither germacrene A nor any other intermediate is released from sesquiterpene synthase active sites during normal catalysis. Evidence to support the intermediacy of germacrene A has been derived from investigations of aristolochene synthases from Aspergillus terreus and Penicillium roquefortii (Cane, D. E. Chem. Rev. 1990, 90, 1089-1103 and ...
WebMar 3, 1998 · The germacrene synthase activity expressed from clone pLE11.3 exceeded the limonene synthase activity by a factor of 10, when measured in the same enzyme … king of all blacks wifeWebDec 17, 2015 · Germacrene A synthase (GAS) from Solidago canadensis catalyzes the conversion of farnesyl diphosphate (FDP) to the plant sesquiterpene (+)-germacrene A. After diphosphate expulsion, farnesyl cation reacts with the distal 10,11-double bond to afford germacrene A (>96%) and 2% α-humulene, which arises from 1,11-cyclization of … luxury horse farms for sale in san diego caWebThe enzyme germacrene-A synthase (EC 4.2.3.23) catalyzes the chemical reaction (2 E ,6 E )-farnesyl diphosphate ⇌ {\displaystyle \rightleftharpoons } (+)-( R )-gemacrene A + … luxury horse farms for sale in michiganWebIn particular, we identified a typical germacrene D synthase gene cluster within the expanded TPS gene family. The entire biosynthetic pathways of germacrenes, (+)-borneol, and (+)-camphor were elucidated in A. argyi. In addition, partial deletion of the amorpha-4,11-diene synthase (ADS) gene and loss of function of ADS homologs may have ... luxury horse farms for sale in caWebSep 20, 2012 · Highlights This manuscript is firstly characterized for germacrene A synthase gene in Citrus species. The gene identification of mono- or sesqui-terpene … luxury horse carriage lancut castleWebMar 3, 2015 · Germacrene A synthase is a two-domain, α−β-terpenoid synthase with the active center in α-domain (C-terminus, 234–558 AA) exhibiting class I terpene synthase activity (Christianson, 2008; Rajabi et al., 2013). β-domain in N-terminus (32–245 AA) has lost the catalytic activity in mono- and sesquiterpene synthases, and seems to play a ... luxury horse farms in flWeb'Germacrene-A synthase' published in 'Class 4–6 Lyases, Isomerases, Ligases' Keywords. Escherichia Coli; Molecular Weight; Catalytic Activity; Functional Analysis kingofallinfo.com